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Epigenetic priming improves salvage chemotherapy in diffuse large B-cell lymphoma via endogenous retrovirus-induced cGAS-STING activation
BACKGROUND: Although most patients with diffuse large B-cell lymphoma (DLBCL) achieve complete remission after first-line rituximab-containing immunochemotherapy, up to 40% of patients relapse and require salvage therapy. Among those patients, a substantial proportion remain refractory to salvage th...
Autores principales: | Liu, Jun, Min, Suji, Kim, Dongchan, Park, Jihyun, Park, Eunchae, Koh, Youngil, Shin, Dong-Yeop, Kim, Tae Kon, Byun, Ja Min, Yoon, Sung-Soo, Hong, Junshik |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10155448/ https://www.ncbi.nlm.nih.gov/pubmed/37138342 http://dx.doi.org/10.1186/s13148-023-01493-x |
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