The G51D SNCA mutation generates a slowly progressive α-synuclein strain in early-onset Parkinson’s disease

Unique strains of α-synuclein aggregates have been postulated to underlie the spectrum of clinical and pathological presentations seen across the synucleinopathies. Whereas multiple system atrophy (MSA) is associated with a predominance of oligodendroglial α-synuclein inclusions, α-synuclein aggrega...

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Detalles Bibliográficos
Autores principales: Lau, Heather H. C., Martinez-Valbuena, Ivan, So, Raphaella W. L., Mehra, Surabhi, Silver, Nicholas R. G., Mao, Alison, Stuart, Erica, Schmitt-Ulms, Cian, Hyman, Bradley T., Ingelsson, Martin, Kovacs, Gabor G., Watts, Joel C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10155462/
https://www.ncbi.nlm.nih.gov/pubmed/37138318
http://dx.doi.org/10.1186/s40478-023-01570-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10155462/
https://www.ncbi.nlm.nih.gov/pubmed/37138318
http://dx.doi.org/10.1186/s40478-023-01570-5

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