Potent immunogenicity and broad-spectrum protection potential of microneedle array patch-based COVID-19 DNA vaccine candidates encoding dimeric RBD chimera of SARS-CoV and SARS-CoV-2 variants

Breakthrough infections by SARS-CoV-2 variants pose a global challenge to COVID-19 pandemic control, and the development of more effective vaccines of broad-spectrum protection is needed. In this study, we constructed pVAX1-based plasmids encoding receptor-binding domain (RBD) chimera of SARS-CoV-1...

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Detalles Bibliográficos
Autores principales: Fan, Feng, Zhang, Xin, Zhang, Zhiyu, Ding, Yuan, Wang, Limei, Xu, Xin, Pan, Yaying, Gong, Fang-Yuan, Jiang, Lin, Kang, Lingyu, Ha, Zhuo, Lu, Huijun, Hou, Jiawang, Kou, Zhihua, Zhao, Gan, Wang, Bin, Gao, Xiao-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Coronaviruses
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10155640/
https://www.ncbi.nlm.nih.gov/pubmed/37038652
http://dx.doi.org/10.1080/22221751.2023.2202269

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10155640/
https://www.ncbi.nlm.nih.gov/pubmed/37038652
http://dx.doi.org/10.1080/22221751.2023.2202269

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