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Ultra High-plex Spatial Proteogenomic Investigation of Giant Cell Glioblastoma Multiforme Immune Infiltrates Reveals Distinct Protein and RNA Expression Profiles

A deeper understanding of complex biological processes, including tumor development and immune response, requires ultra high-plex, spatial interrogation of multiple “omes”. Here we present the development and implementation of a novel spatial proteogenomic (SPG) assay on the GeoMx Digital Spatial Pr...

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Detalles Bibliográficos
Autores principales: Bonnett, Shilah A., Rosenbloom, Alyssa B., Ong, Giang T., Conner, Mark, Rininger, Aric B.E., Newhouse, Daniel, New, Felicia, Phan, Chi Q., Ilcisin, Saskia, Sato, Hiromi, Lyssand, John S., Geiss, Gary, Beechem, Joseph M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10155752/
https://www.ncbi.nlm.nih.gov/pubmed/37377888
http://dx.doi.org/10.1158/2767-9764.CRC-22-0396