Mechanism of signal-anchor triage during early steps of membrane protein insertion

Most membrane proteins use their first transmembrane domain, known as a signal anchor (SA), for co-translational targeting to the endoplasmic reticulum (ER) via the signal recognition particle (SRP). The SA then inserts into the membrane using either the Sec61 translocation channel or the ER membran...

Descripción completa

Detalles Bibliográficos
Autores principales: Wu, Haoxi, Hegde, Ramanujan S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10155758/
https://www.ncbi.nlm.nih.gov/pubmed/36764302
http://dx.doi.org/10.1016/j.molcel.2023.01.018

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10155758/
https://www.ncbi.nlm.nih.gov/pubmed/36764302
http://dx.doi.org/10.1016/j.molcel.2023.01.018

Ejemplares similares