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Mechanism of signal-anchor triage during early steps of membrane protein insertion
Most membrane proteins use their first transmembrane domain, known as a signal anchor (SA), for co-translational targeting to the endoplasmic reticulum (ER) via the signal recognition particle (SRP). The SA then inserts into the membrane using either the Sec61 translocation channel or the ER membran...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Cell Press
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10155758/ https://www.ncbi.nlm.nih.gov/pubmed/36764302 http://dx.doi.org/10.1016/j.molcel.2023.01.018 |