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An immunoinformatic approach to assessing the immunogenic capacity of alpha-neurotoxins in elapid snake venoms

Introduction: Most elapid snakes produce venoms that contain alpha-neurotoxins (α-NTXs), which are proteins that cause post-synaptic blockade and paralysis in snakebite envenoming. However, existing elapid antivenoms are known for their low potency in neutralizing the neurotoxic activity of α-NTXs,...

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Detalles Bibliográficos
Autores principales: Chan, Yi Wei, Tan, Choo Hock, Heh, Choon Han, Tan, Kae Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10155835/
https://www.ncbi.nlm.nih.gov/pubmed/37153801
http://dx.doi.org/10.3389/fphar.2023.1143437