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“Super” SERPINs—A stabilizing force against fibrinolysis in thromboinflammatory conditions

The superfamily of serine protease inhibitors (SERPINs) are a class of inhibitors that utilise a dynamic conformational change to trap and inhibit their target enzymes. Their powerful nature lends itself well to regulation of complex physiological enzymatic cascades, such as the haemostatic, inflamm...

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Detalles Bibliográficos
Autores principales: Humphreys, Steven J., Whyte, Claire S., Mutch, Nicola J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10155837/
https://www.ncbi.nlm.nih.gov/pubmed/37153474
http://dx.doi.org/10.3389/fcvm.2023.1146833