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“Super” SERPINs—A stabilizing force against fibrinolysis in thromboinflammatory conditions
The superfamily of serine protease inhibitors (SERPINs) are a class of inhibitors that utilise a dynamic conformational change to trap and inhibit their target enzymes. Their powerful nature lends itself well to regulation of complex physiological enzymatic cascades, such as the haemostatic, inflamm...
Autores principales: | Humphreys, Steven J., Whyte, Claire S., Mutch, Nicola J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10155837/ https://www.ncbi.nlm.nih.gov/pubmed/37153474 http://dx.doi.org/10.3389/fcvm.2023.1146833 |
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