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Closing the Gap: An Atomistic Structural and Functional Perspective of S. mansoni Universal Stress G4LZI3 Protein in Complex with Phenolic Compounds

BACKGROUND: For decades, Praziquantel has been the undisputed drug of choice for all schistosome infections, but rising concerns due to the unelucidated mechanism of action of the drug and unavoidable reports of emerging drug resistant strains has necessitated the need for alternative treatment drug...

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Detalles Bibliográficos
Autores principales: Masamba, Priscilla, Munsamy, Geraldene, Kappo, Abidemi Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10155883/
https://www.ncbi.nlm.nih.gov/pubmed/33001015
http://dx.doi.org/10.2174/1570163817666201001122436