Development of fluorogenic substrates for colorectal tumor-related neuropeptidases for activity-based diagnosis

The M3 metalloproteases, neurolysin and THOP1, are neuropeptidases that are expressed in various tissues and metabolize neuropeptides, such as neurotensin. The biological roles of these enzymes are not well characterized, partially because the chemical tools to analyse their activities are not well...

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Detalles Bibliográficos
Autores principales: Nagano, Norimichi, Ichihashi, Yuki, Komatsu, Toru, Matsuzaki, Hiroyuki, Hata, Keisuke, Watanabe, Toshiaki, Misawa, Yoshihiro, Suzuki, Misa, Sakamoto, Shingo, Kagami, Yu, Kashiro, Ayumi, Takeuchi, Keiko, Kanemitsu, Yukihide, Ochiai, Hiroki, Watanabe, Rikiya, Honda, Kazufumi, Urano, Yasuteru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10155908/
https://www.ncbi.nlm.nih.gov/pubmed/37152255
http://dx.doi.org/10.1039/d2sc07029d

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10155908/
https://www.ncbi.nlm.nih.gov/pubmed/37152255
http://dx.doi.org/10.1039/d2sc07029d

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