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Development of fluorogenic substrates for colorectal tumor-related neuropeptidases for activity-based diagnosis
The M3 metalloproteases, neurolysin and THOP1, are neuropeptidases that are expressed in various tissues and metabolize neuropeptides, such as neurotensin. The biological roles of these enzymes are not well characterized, partially because the chemical tools to analyse their activities are not well...
Autores principales: | Nagano, Norimichi, Ichihashi, Yuki, Komatsu, Toru, Matsuzaki, Hiroyuki, Hata, Keisuke, Watanabe, Toshiaki, Misawa, Yoshihiro, Suzuki, Misa, Sakamoto, Shingo, Kagami, Yu, Kashiro, Ayumi, Takeuchi, Keiko, Kanemitsu, Yukihide, Ochiai, Hiroki, Watanabe, Rikiya, Honda, Kazufumi, Urano, Yasuteru |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10155908/ https://www.ncbi.nlm.nih.gov/pubmed/37152255 http://dx.doi.org/10.1039/d2sc07029d |
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