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Quantifying cooperative multisite binding in the hub protein LC8 through Bayesian inference

Multistep protein-protein interactions underlie most biological processes, but their characterization through methods such as isothermal titration calorimetry (ITC) is largely confined to simple models that provide little information on the intermediate, individual steps. In this study, we primarily...

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Detalles Bibliográficos
Autores principales: Estelle, Aidan B., George, August, Barbar, Elisar J., Zuckerman, Daniel M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10155966/
https://www.ncbi.nlm.nih.gov/pubmed/37083599
http://dx.doi.org/10.1371/journal.pcbi.1011059