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Characterization of GSDME in amphioxus provides insights into the functional evolution of GSDM-mediated pyroptosis

Members of the gasdermin (GSDM) family are pore-forming effectors that cause membrane permeabilization and pyroptosis, a lytic proinflammatory type of cell death. To reveal the functional evolution of GSDM-mediated pyroptosis at the transition from invertebrates to vertebrates, we conducted function...

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Detalles Bibliográficos
Autores principales: Wang, Xinli, Wei, Xuxia, Lu, Yan, Wang, Qinghuan, Fu, Rong, Wang, Yin, Wang, Qin, Wang, Xiangyan, Chen, Shangwu, Xu, Anlong, Yuan, Shaochun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10155998/
https://www.ncbi.nlm.nih.gov/pubmed/37134086
http://dx.doi.org/10.1371/journal.pbio.3002062