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Characterization of GSDME in amphioxus provides insights into the functional evolution of GSDM-mediated pyroptosis
Members of the gasdermin (GSDM) family are pore-forming effectors that cause membrane permeabilization and pyroptosis, a lytic proinflammatory type of cell death. To reveal the functional evolution of GSDM-mediated pyroptosis at the transition from invertebrates to vertebrates, we conducted function...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10155998/ https://www.ncbi.nlm.nih.gov/pubmed/37134086 http://dx.doi.org/10.1371/journal.pbio.3002062 |