Multiplexed selectivity screening of anti-GPCR antibodies

G protein–coupled receptors (GPCRs) control critical cellular signaling pathways. Therapeutic agents including anti-GPCR antibodies (Abs) are being developed to modulate GPCR function. However, validating the selectivity of anti-GPCR Abs is challenging because of sequence similarities among individu...

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Detalles Bibliográficos
Autores principales: Dahl, Leo, Kotliar, Ilana B., Bendes, Annika, Dodig-Crnković, Tea, Fromm, Samuel, Elofsson, Arne, Uhlén, Mathias, Sakmar, Thomas P., Schwenk, Jochen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10156119/
https://www.ncbi.nlm.nih.gov/pubmed/37134173
http://dx.doi.org/10.1126/sciadv.adf9297

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10156119/
https://www.ncbi.nlm.nih.gov/pubmed/37134173
http://dx.doi.org/10.1126/sciadv.adf9297

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