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Inter-organelle cross-talk supports acetyl-coenzyme A homeostasis and lipogenesis under metabolic stress

Proliferating cells rely on acetyl-CoA to support membrane biogenesis and acetylation. Several organelle-specific pathways are available for provision of acetyl-CoA as nutrient availability fluctuates, so understanding how cells maintain acetyl-CoA homeostasis under such stresses is critically impor...

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Detalles Bibliográficos
Autores principales: Kuna, Ramya S., Kumar, Avi, Wessendorf-Rodriguez, Karl A., Galvez, Hector, Green, Courtney R., McGregor, Grace H., Cordes, Thekla, Shaw, Reuben J., Svensson, Robert U., Metallo, Christian M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10156121/
https://www.ncbi.nlm.nih.gov/pubmed/37134162
http://dx.doi.org/10.1126/sciadv.adf0138