Cargando…
Inter-organelle cross-talk supports acetyl-coenzyme A homeostasis and lipogenesis under metabolic stress
Proliferating cells rely on acetyl-CoA to support membrane biogenesis and acetylation. Several organelle-specific pathways are available for provision of acetyl-CoA as nutrient availability fluctuates, so understanding how cells maintain acetyl-CoA homeostasis under such stresses is critically impor...
Autores principales: | Kuna, Ramya S., Kumar, Avi, Wessendorf-Rodriguez, Karl A., Galvez, Hector, Green, Courtney R., McGregor, Grace H., Cordes, Thekla, Shaw, Reuben J., Svensson, Robert U., Metallo, Christian M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10156121/ https://www.ncbi.nlm.nih.gov/pubmed/37134162 http://dx.doi.org/10.1126/sciadv.adf0138 |
Ejemplares similares
-
Acetylcarnitine shuttling links mitochondrial metabolism to histone acetylation and lipogenesis
por: Izzo, Luke T., et al.
Publicado: (2023) -
Itaconate Alters Succinate and Coenzyme A Metabolism via Inhibition of Mitochondrial Complex II and Methylmalonyl-CoA Mutase
por: Cordes, Thekla, et al.
Publicado: (2021) -
Peroxisome function relies on organelle-associated mRNA translation
por: Dahan, Noa, et al.
Publicado: (2022) -
Progressive alterations in amino acid and lipid metabolism correlate with peripheral neuropathy in Polg(D257A) mice
por: Lim, Esther W., et al.
Publicado: (2021) -
Membraneless organelles formed by liquid-liquid phase separation increase bacterial fitness
por: Jin, Xin, et al.
Publicado: (2021)