CHD-associated enhancers shape human cardiomyocyte lineage commitment

Enhancers orchestrate gene expression programs that drive multicellular development and lineage commitment. Thus, genetic variants at enhancers are thought to contribute to developmental diseases by altering cell fate commitment. However, while many variant-containing enhancers have been identified,...

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Detalles Bibliográficos
Autores principales: Armendariz, Daniel A, Goetsch, Sean C, Sundarrajan, Anjana, Sivakumar, Sushama, Wang, Yihan, Xie, Shiqi, Munshi, Nikhil V, Hon, Gary C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Genetics and Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10156167/
https://www.ncbi.nlm.nih.gov/pubmed/37096669
http://dx.doi.org/10.7554/eLife.86206

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10156167/
https://www.ncbi.nlm.nih.gov/pubmed/37096669
http://dx.doi.org/10.7554/eLife.86206

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