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Parenteral succinate reduces levels of reactive oxygen species without changing serum caspase-3 levels in septic rats

BACKGROUND: Sepsis is a syndrome of physiological, pathological, and biochemical disorders with several processes co-occurring; reactive oxygen species (ROS) production and apoptosis are 2 of them. Succinate is a Krebs cycle intermediate that is oxydized in complex II of the mitochondria. This study...

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Detalles Bibliográficos
Autores principales: Chapela, Sebastián, Muscogiuri, Giovanna, Barrea, Luigi, Frias-Toral, Evelyn, Burgos, Hilda, Ricart, María Cecilia, Muryan, Alexis, Schiel, Amalia, Alonso, Manuel, Stella, Carlos Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10156549/
https://www.ncbi.nlm.nih.gov/pubmed/36734445
http://dx.doi.org/10.5114/ait.2022.122549