Visualizing the disordered nuclear transport machinery in situ

The approximately 120 MDa mammalian nuclear pore complex (NPC) acts as a gatekeeper for the transport between the nucleus and cytosol(1). The central channel of the NPC is filled with hundreds of intrinsically disordered proteins (IDPs) called FG-nucleoporins (FG-NUPs)(2,3). Although the structure o...

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Detalles Bibliográficos
Autores principales: Yu, Miao, Heidari, Maziar, Mikhaleva, Sofya, Tan, Piau Siong, Mingu, Sara, Ruan, Hao, Reinkemeier, Christopher D., Obarska-Kosinska, Agnieszka, Siggel, Marc, Beck, Martin, Hummer, Gerhard, Lemke, Edward A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10156602/
https://www.ncbi.nlm.nih.gov/pubmed/37100914
http://dx.doi.org/10.1038/s41586-023-05990-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10156602/
https://www.ncbi.nlm.nih.gov/pubmed/37100914
http://dx.doi.org/10.1038/s41586-023-05990-0

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