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mRNA decoding in human is kinetically and structurally distinct from bacteria

In all species, ribosomes synthesize proteins by faithfully decoding messenger RNA (mRNA) nucleotide sequences using aminoacyl-tRNA substrates. Current knowledge of the decoding mechanism derives principally from studies on bacterial systems(1). Although key features are conserved across evolution(2...

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Detalles Bibliográficos
Autores principales: Holm, Mikael, Natchiar, S. Kundhavai, Rundlet, Emily J., Myasnikov, Alexander G., Watson, Zoe L., Altman, Roger B., Wang, Hao-Yuan, Taunton, Jack, Blanchard, Scott C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10156603/
https://www.ncbi.nlm.nih.gov/pubmed/37020024
http://dx.doi.org/10.1038/s41586-023-05908-w