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Administration of prosaposin-derived neurotrophic factor to neural tube defects facilitates regeneration and restores neurological functions

Neural tube defects (NTDs) cause fetal and pediatric deaths or lifelong neurological disabilities. No effective treatment is currently available for NTDs. We attempted to elucidate the pathogenesis of NTDs and propose a therapeutic strategy. Intra-amniotic treatment with prosaposin-derived 18-mer pe...

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Detalles Bibliográficos
Autores principales: Khan, Sakirul, Takeuchi, Akihide, Nabeka, Hiroaki, Khan, Farzana, Shimokawa, Tetsuya, Takanezawa, Sota, Saitou, Takashi, Imamura, Takeshi, Tachibana, Tetsuya, Nishizono, Akira, Hamada, Fumihiko, Matsuda, Seiji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10156616/
https://www.ncbi.nlm.nih.gov/pubmed/37153447
http://dx.doi.org/10.1016/j.isci.2023.106277