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Role of paraoxonase 1 activity and PON1 gene polymorphisms in sickle cell disease

Sickle cell disease (SCD) patients often exhibit a dyslipidemic sub-phenotype. Paraoxonase 1 (PON 1) is a serum glycoprotein associated with the high-density lipoproteins cholesterol (HDL-C), and variability in PON1 activity depends on the PON1 genotypes. We investigated the influence of PON1c.192Q ...

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Detalles Bibliográficos
Autores principales: Menezes, Joelma Figueiredo, Carvalho, Magda Oliveira Seixas, Rocha, Larissa Carneiro, dos Santos, Felipe Miranda, Adorno, Elisângela Vitória, de Souza, Cyntia Cajado, Santiago, Rayra Pereira, da Guarda, Caroline Conceição, de Oliveira, Rodrigo Mota, Figueiredo, Camylla Vilas Boas, Carvalho, Suéllen Pinheiro, Yahouédéhou, Sètondji Cocou Modeste Alexandre, Fiuza, Luciana Magalhães, Adanho, Corynne Stéphanie Ahouefa, Pitanga, Thassila Nogueira, Lyra, Isa Menezes, Nascimento, Valma Maria Lopes, Noronha-Dutra, Alberto Augusto, Goncalves, Marilda Souza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10156724/
https://www.ncbi.nlm.nih.gov/pubmed/37137941
http://dx.doi.org/10.1038/s41598-023-34396-1