HNF1A binds and regulates the expression of SLC51B to facilitate the uptake of estrone sulfate in human renal proximal tubule epithelial cells

Renal defects in maturity onset diabetes of the young 3 (MODY3) patients and Hnf1a(-/-) mice suggest an involvement of HNF1A in kidney development and/or its function. Although numerous studies have leveraged on Hnf1α(-/-) mice to infer some transcriptional targets and function of HNF1A in mouse kid...

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Detalles Bibliográficos
Autores principales: Chan, Jun Wei, Neo, Claire Wen Ying, Ghosh, Soumita, Choi, Hyungwon, Lim, Su Chi, Tai, E. Shyong, Teo, Adrian Kee Keong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10156747/
https://www.ncbi.nlm.nih.gov/pubmed/37137894
http://dx.doi.org/10.1038/s41419-023-05827-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10156747/
https://www.ncbi.nlm.nih.gov/pubmed/37137894
http://dx.doi.org/10.1038/s41419-023-05827-8

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