Loss of function of FIP200 in human pluripotent stem cell-derived neurons leads to axonal pathology and hyperactivity

FIP200 plays important roles in homeostatic processes such as autophagy and signaling pathways such as focal adhesion kinase (FAK) signaling. Furthermore, genetic studies suggest an association of FIP200 mutations with psychiatric disorders. However, its potential connections to psychiatric disorder...

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Detalles Bibliográficos
Autores principales: Wen, Jianbin, Zellner, Andreas, Braun, Nils Christian, Bajaj, Thomas, Gassen, Nils Christian, Peitz, Michael, Brüstle, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10156752/
https://www.ncbi.nlm.nih.gov/pubmed/37137886
http://dx.doi.org/10.1038/s41398-023-02432-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10156752/
https://www.ncbi.nlm.nih.gov/pubmed/37137886
http://dx.doi.org/10.1038/s41398-023-02432-3

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