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Loss of function of FIP200 in human pluripotent stem cell-derived neurons leads to axonal pathology and hyperactivity
FIP200 plays important roles in homeostatic processes such as autophagy and signaling pathways such as focal adhesion kinase (FAK) signaling. Furthermore, genetic studies suggest an association of FIP200 mutations with psychiatric disorders. However, its potential connections to psychiatric disorder...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10156752/ https://www.ncbi.nlm.nih.gov/pubmed/37137886 http://dx.doi.org/10.1038/s41398-023-02432-3 |