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Molecular architecture of the Gα(i)-bound TRPC5 ion channel

G-protein coupled receptors (GPCRs) and ion channels serve as key molecular switches through which extracellular stimuli are transformed into intracellular effects, and it has long been postulated that ion channels are direct effector molecules of the alpha subunit of G-proteins (Gα). However, no co...

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Detalles Bibliográficos
Autores principales: Won, Jongdae, Kim, Jinsung, Jeong, Hyeongseop, Kim, Jinhyeong, Feng, Shasha, Jeong, Byeongseok, Kwak, Misun, Ko, Juyeon, Im, Wonpil, So, Insuk, Lee, Hyung Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10156788/
https://www.ncbi.nlm.nih.gov/pubmed/37137991
http://dx.doi.org/10.1038/s41467-023-38281-3