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The structure and evolutionary diversity of the fungal E3-binding protein
The pyruvate dehydrogenase complex (PDC) is a central metabolic enzyme in all living cells composed majorly of E1, E2, and E3. Tight coupling of their reactions makes each component essential, so that any loss impacts oxidative metabolism pathologically. E3 retention is mediated by the E3-binding pr...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Nature Publishing Group UK
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10156792/ https://www.ncbi.nlm.nih.gov/pubmed/37137945 http://dx.doi.org/10.1038/s42003-023-04854-7 |