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Mechanism of assembly, activation and lysine selection by the SIN3B histone deacetylase complex
Lysine acetylation in histone tails is a key post-translational modification that controls transcription activation. Histone deacetylase complexes remove histone acetylation, thereby repressing transcription and regulating the transcriptional output of each gene. Although these complexes are drug ta...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10156912/ https://www.ncbi.nlm.nih.gov/pubmed/37137925 http://dx.doi.org/10.1038/s41467-023-38276-0 |