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Mechanism of assembly, activation and lysine selection by the SIN3B histone deacetylase complex

Lysine acetylation in histone tails is a key post-translational modification that controls transcription activation. Histone deacetylase complexes remove histone acetylation, thereby repressing transcription and regulating the transcriptional output of each gene. Although these complexes are drug ta...

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Detalles Bibliográficos
Autores principales: Wan, Mandy S. M., Muhammad, Reyhan, Koliopoulos, Marios G., Roumeliotis, Theodoros I., Choudhary, Jyoti S., Alfieri, Claudio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10156912/
https://www.ncbi.nlm.nih.gov/pubmed/37137925
http://dx.doi.org/10.1038/s41467-023-38276-0