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The α2δ-1-NMDA receptor complex and its potential as a therapeutic target for ischemic stroke

N-methyl-(D)-aspartate receptors (NMDARs) play a critical role in excitotoxicity caused by ischemic stroke, but NMDAR antagonists have failed to be translated into clinical practice for treating stroke patients. Recent studies suggest that targeting the specific protein–protein interactions that reg...

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Detalles Bibliográficos
Autores principales: Wu, Tao, Chen, Shao-Rui, Pan, Hui-Lin, Luo, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10157046/
https://www.ncbi.nlm.nih.gov/pubmed/37153659
http://dx.doi.org/10.3389/fneur.2023.1148697