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Clonogenicity-based radioresistance determines the expression of immune suppressive immune checkpoint molecules after hypofractionated irradiation of MDA-MB-231 triple-negative breast cancer cells

Only a subset of patients with triple-negative breast cancer (TNBC) benefits from a combination of radio- (RT) and immunotherapy. Therefore, we aimed to examine the impact of radioresistance and brain metastasizing potential on the immunological phenotype of TNBC cells following hypofractionated RT...

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Detalles Bibliográficos
Autores principales: Gehre, Simon, Meyer, Felix, Sengedorj, Azzaya, Grottker, Fridolin, Reichardt, Clara M., Alomo, Jannik, Borgmann, Kerstin, Frey, Benjamin, Fietkau, Rainer, Rückert, Michael, Gaipl, Udo S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10157086/
https://www.ncbi.nlm.nih.gov/pubmed/37152024
http://dx.doi.org/10.3389/fonc.2023.981239