Cargando…

Clonogenicity-based radioresistance determines the expression of immune suppressive immune checkpoint molecules after hypofractionated irradiation of MDA-MB-231 triple-negative breast cancer cells

Only a subset of patients with triple-negative breast cancer (TNBC) benefits from a combination of radio- (RT) and immunotherapy. Therefore, we aimed to examine the impact of radioresistance and brain metastasizing potential on the immunological phenotype of TNBC cells following hypofractionated RT...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gehre, Simon, Meyer, Felix, Sengedorj, Azzaya, Grottker, Fridolin, Reichardt, Clara M., Alomo, Jannik, Borgmann, Kerstin, Frey, Benjamin, Fietkau, Rainer, Rückert, Michael, Gaipl, Udo S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10157086/ https://www.ncbi.nlm.nih.gov/pubmed/37152024 http://dx.doi.org/10.3389/fonc.2023.981239

Ejemplares similares

Radiotherapy combined with docetaxel alters the immune phenotype of HNSCC cells and results in increased surface expression of CD137 and release of HMGB1 of specifically HPV-positive tumor cells
por: Grottker, Fridolin, et al.
Publicado: (2023)

Head and neck tumor cells treated with hypofractionated irradiation die via apoptosis and are better taken up by M1-like macrophages
por: Wedekind, Hanna, et al.
Publicado: (2021)

The Effect of Hyperthermia and Radiotherapy Sequence on Cancer Cell Death and the Immune Phenotype of Breast Cancer Cells
por: Sengedorj, Azzaya, et al.
Publicado: (2022)

Hypofractionated Radiotherapy Upregulates Several Immune Checkpoint Molecules in Head and Neck Squamous Cell Carcinoma Cells Independently of the HPV Status While ICOS-L Is Upregulated Only on HPV-Positive Cells
por: Wimmer, Sebastian, et al.
Publicado: (2021)

Hypofractionated Irradiation Has Immune Stimulatory Potential and Induces a Timely Restricted Infiltration of Immune Cells in Colon Cancer Tumors
por: Frey, Benjamin, et al.
Publicado: (2017)

Long non-coding RNA HOTAIR enhances radioresistance in MDA-MB231 breast cancer cells
por: Zhou, Yun, et al.
Publicado: (2017)

Potential Effects of Chrysin on MDA-MB-231 Cells
por: Hong, Teh Ban, et al.
Publicado: (2010)

Loquat (Eriobotrya japonica) leaf extract inhibits the growth of MDA-MB-231 tumors in nude mouse xenografts and invasion of MDA-MB-231 cells
por: You, Mi-Kyoung, et al.
Publicado: (2016)

Citral induced apoptosis in MDA-MB-231 spheroid cells
por: Nigjeh, Siyamak Ebrahimi, et al.
Publicado: (2018)

Shock wave impact on the viability of MDA-MB-231 cells
por: Liao, Yingqian, et al.
Publicado: (2020)

Effects of FSTL1 on cell proliferation in breast cancer cell line MDA-MB-231 and its brain metastatic variant MDA-MB-231-BR
por: An, Jiaqiang, et al.
Publicado: (2017)

Temporin-GHb of Hylarana guentheri induces apoptosis by the mitochondrial pathway in MDA-MB-231 cells : Temporin-GHb induces MDA-MB-231 cell apoptosis
por: Liu, Yujun, et al.
Publicado: (2022)

Action and Signaling of Lysophosphatidylethanolamine in MDA-MB-231 Breast Cancer Cells
por: Park, Soo-Jin, et al.
Publicado: (2014)

Hypoxia regulates stemness of breast cancer MDA-MB-231 cells
por: Xie, Jing, et al.
Publicado: (2016)

Berberine Inhibits MDA-MB-231 Cells by Attenuating Their Inflammatory Responses
por: Zhao, Lina, et al.
Publicado: (2020)

Dehydrocorydaline inhibits the tumorigenesis of breast cancer MDA-MB-231 cells
por: Huang, Ying, et al.
Publicado: (2020)

Combinations of Radiotherapy with Vaccination and Immune Checkpoint Inhibition Differently Affect Primary and Abscopal Tumor Growth and the Tumor Microenvironment
por: Rückert, Michael, et al.
Publicado: (2021)

Effects of osteopontin inhibition on radiosensitivity of MDA-MB-231 breast cancer cells
por: Hahnel, Antje, et al.
Publicado: (2010)

Anti-Cancer Effect of IN-2001 in MDA-MB-231 Human Breast Cancer
por: Min, Kyung Nan, et al.
Publicado: (2012)

STAT3 Knockdown Induces Tumor Formation by MDA-MB-231 Cells
por: Banerjee, Kasturi, et al.
Publicado: (2018)

Synergistic action of cisplatin and echistatin in MDA-MB-231 breast cancer cells
por: Czarnomysy, Robert, et al.
Publicado: (2016)

Proteomics Profiling of KAIMRC1 in Comparison to MDA-MB231 and MCF-7
por: Alghanem, Bandar, et al.
Publicado: (2020)

Effects of curcumin complexes on MDA-MB-231 breast cancer cell proliferation
por: Mohammed, Fatima, et al.
Publicado: (2020)

Datasets of in vitro clonogenic assays showing low dose hyper-radiosensitivity and induced radioresistance
por: Polgár, Szabolcs, et al.
Publicado: (2022)

Smad2/3-Regulated Expression of DLX2 Is Associated with Radiation-Induced Epithelial-Mesenchymal Transition and Radioresistance of A549 and MDA-MB-231 Human Cancer Cell Lines
por: Choi, Yeo-Jin, et al.
Publicado: (2016)

Development of Resistance towards Artesunate in MDA-MB-231 Human Breast Cancer Cells
por: Bachmeier, Beatrice, et al.
Publicado: (2011)

Polyphenols Sensitization Potentiates Susceptibility of MCF-7 and MDA MB-231 Cells to Centchroman
por: Singh, Neetu, et al.
Publicado: (2012)

Phenotypic Switch Induced by Simulated Microgravity on MDA-MB-231 Breast Cancer Cells
por: Masiello, Maria Grazia, et al.
Publicado: (2014)

Effects of Lovastatin on MDA-MB-231 Breast Cancer Cells: An Antibody Microarray Analysis
por: Yang, Tao, et al.
Publicado: (2016)

Optimized Method for Untargeted Metabolomics Analysis of MDA-MB-231 Breast Cancer Cells
por: Peterson, Amanda L., et al.
Publicado: (2016)

Antitumor effects of Xi Huang pills on MDA-MB-231 cells in vitro and in vivo
por: Zheng, Wenxian, et al.
Publicado: (2018)

Elastin molecular aging promotes MDA‐MB‐231 breast cancer cell invasiveness
por: Salesse, Stéphanie, et al.
Publicado: (2018)

Allyl Isothiocyanate Exhibits No Anticancer Activity in MDA-MB-231 Breast Cancer Cells
por: Sayeed, Md. Abu, et al.
Publicado: (2018)

Ginseng polysaccharide inhibits MDA-MB-231 cell proliferation by activating the inflammatory response
por: Zhou, Haoliang, et al.
Publicado: (2020)

Characterization of Triple-Negative Breast Cancer MDA-MB-231 Cell Spheroid Model
por: Huang, Zhaoming, et al.
Publicado: (2020)

Mannoside-Modified Branched Gold Nanoparticles for Photothermal Therapy to MDA-MB-231 Cells
por: Lin, Han-Chen, et al.
Publicado: (2020)

Arctigenin Enhances the Cytotoxic Effect of Doxorubicin in MDA-MB-231 Breast Cancer Cells
por: Lee, Kyu-Shik, et al.
Publicado: (2020)

Amikacin Suppresses Human Breast Cancer Cell MDA-MB-231 Migration and Invasion
por: Wang, Yun-Hsin, et al.
Publicado: (2020)

Flavokawain B induced cytotoxicity in two breast cancer cell lines, MCF-7 and MDA-MB231 and inhibited the metastatic potential of MDA-MB231 via the regulation of several tyrosine kinases In vitro
por: Abu, Nadiah, et al.
Publicado: (2016)

PRIMA-1(MET) Does Not Restore Vitamin D Sensitivity to MDA-MB-231 and MDA-MB-468 Triple-Negative Breast Cancer Cells
por: Kotob, Shadi N., et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_ehumq4c9gonua8gig2t7668hch