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c-Maf-positive spinal cord neurons are critical elements of a dorsal horn circuit for mechanical hypersensitivity in neuropathy

Corticospinal tract (CST) neurons innervate the deep spinal dorsal horn to sustain chronic neuropathic pain. The majority of neurons targeted by the CST are interneurons expressing the transcription factor c-Maf. Here, we used intersectional genetics to decipher the function of these neurons in dors...

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Detalles Bibliográficos
Autores principales: Frezel, Noémie, Ranucci, Matteo, Foster, Edmund, Wende, Hagen, Pelczar, Pawel, Mendes, Raquel, Ganley, Robert P., Werynska, Karolina, d’Aquin, Simon, Beccarini, Camilla, Birchmeier, Carmen, Zeilhofer, Hanns Ulrich, Wildner, Hendrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10157139/
https://www.ncbi.nlm.nih.gov/pubmed/36947543
http://dx.doi.org/10.1016/j.celrep.2023.112295