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c-Maf-positive spinal cord neurons are critical elements of a dorsal horn circuit for mechanical hypersensitivity in neuropathy
Corticospinal tract (CST) neurons innervate the deep spinal dorsal horn to sustain chronic neuropathic pain. The majority of neurons targeted by the CST are interneurons expressing the transcription factor c-Maf. Here, we used intersectional genetics to decipher the function of these neurons in dors...
Autores principales: | Frezel, Noémie, Ranucci, Matteo, Foster, Edmund, Wende, Hagen, Pelczar, Pawel, Mendes, Raquel, Ganley, Robert P., Werynska, Karolina, d’Aquin, Simon, Beccarini, Camilla, Birchmeier, Carmen, Zeilhofer, Hanns Ulrich, Wildner, Hendrik |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10157139/ https://www.ncbi.nlm.nih.gov/pubmed/36947543 http://dx.doi.org/10.1016/j.celrep.2023.112295 |
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