ECSIT is essential for RANKL-induced stimulation of mitochondria in osteoclasts and a target for the anti-osteoclastogenic effects of estrogens

INTRODUCTION: Estrogens inhibit bone resorption and preserve bone mass, at least in part, via direct effects on osteoclasts. The binding of RANKL, the critical cytokine for osteoclast differentiation, to its receptor in osteoclast precursor cells of the monocyte lineage recruits the adaptor protein...

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Detalles Bibliográficos
Autores principales: Marques-Carvalho, Adriana, Sardão, Vilma A., Kim, Ha-Neui, Almeida, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10157190/
https://www.ncbi.nlm.nih.gov/pubmed/37152948
http://dx.doi.org/10.3389/fendo.2023.1110369

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10157190/
https://www.ncbi.nlm.nih.gov/pubmed/37152948
http://dx.doi.org/10.3389/fendo.2023.1110369

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