Proof-of-concept for effective antiviral activity of an in silico designed decoy synthetic mRNA against SARS-CoV-2 in the Vero E6 cell-based infection model

The positive-sense single-stranded (ss) RNA viruses of the Betacoronavirus (beta-CoV) genus can spillover from mammals to humans and are an ongoing threat to global health and commerce, as demonstrated by the current zoonotic pandemic of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)....

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Detalles Bibliográficos
Autores principales: Atari, Nofar, Erster, Oran, Shteinberg, Yair Heskiau, Asraf, Hadar, Giat, Eitan, Mandelboim, Michal, Goldstein, Itamar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10157240/
https://www.ncbi.nlm.nih.gov/pubmed/37152730
http://dx.doi.org/10.3389/fmicb.2023.1113697

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10157240/
https://www.ncbi.nlm.nih.gov/pubmed/37152730
http://dx.doi.org/10.3389/fmicb.2023.1113697

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