Astrocytes mediate cell non-autonomous correction of aberrant firing in human FXS neurons

Pre-clinical studies of fragile X syndrome (FXS) have focused on neurons, with the role of glia remaining largely underexplored. We examined the astrocytic regulation of aberrant firing of FXS neurons derived from human pluripotent stem cells. Human FXS cortical neurons, co-cultured with human FXS a...

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Detalles Bibliográficos
Autores principales: Sharma, Shreya Das, Reddy, Bharath Kumar, Pal, Rakhi, Ritakari, Tuula E., Cooper, James D., Selvaraj, Bhuvaneish T., Kind, Peter C., Chandran, Siddharthan, Wyllie, David J.A., Chattarji, Sumantra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10157295/
https://www.ncbi.nlm.nih.gov/pubmed/37018073
http://dx.doi.org/10.1016/j.celrep.2023.112344

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10157295/
https://www.ncbi.nlm.nih.gov/pubmed/37018073
http://dx.doi.org/10.1016/j.celrep.2023.112344

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