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Transient suppression of SUMOylation in embryonic stem cells generates embryo-like structures

Recent advances in synthetic embryology have opened new avenues for understanding the complex events controlling mammalian peri-implantation development. Here, we show that mouse embryonic stem cells (ESCs) solely exposed to chemical inhibition of SUMOylation generate embryo-like structures comprisi...

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Detalles Bibliográficos
Autores principales: Cossec, Jack-Christophe, Traboulsi, Tatiana, Sart, Sébastien, Loe-Mie, Yann, Guthmann, Manuel, Hendriks, Ivo A., Theurillat, Ilan, Nielsen, Michael L., Torres-Padilla, Maria-Elena, Baroud, Charles N., Dejean, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10157296/
https://www.ncbi.nlm.nih.gov/pubmed/37061916
http://dx.doi.org/10.1016/j.celrep.2023.112380