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Inhibition of ATM kinase rescues planarian regeneration after lethal radiation

As stem cells divide, they acquire mutations that can be passed on to daughter cells. To mitigate potentially deleterious outcomes, cells activate the DNA damage response (DDR) network, which governs several cellular outcomes following DNA damage, including repairing DNA or undergoing apoptosis. At...

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Detalles Bibliográficos
Autores principales: Shiroor, Divya A, Wang, Kuang‐Tse, Sanketi, Bhargav D, Tapper, Justin K, Adler, Carolyn E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10157310/
https://www.ncbi.nlm.nih.gov/pubmed/36943023
http://dx.doi.org/10.15252/embr.202256112