Nuclear localization of human MEIOB requires its NLS in the OB domain and interaction with SPATA22: Human SPATA22 assists MEIOB to enter the nucleus

MEIOB is a vital protein in meiotic homologous recombination and plays an indispensable role in human gametogenesis. In mammals, MEIOB and its partner SPATA22 form a heterodimer, ensuring their effective localization on single-strand DNA (ssDNA) and proper synapsis processes. Mutations in human MEIO...

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Detalles Bibliográficos
Autores principales: Xu, Yating, Chen, Zhen, Wu, Panfeng, Qu, Wei, Shi, Hanqing, Cheng, Muyang, Xu, Yumin, Jin, Tingyu, Liu, Cong, Li, Yi, Luo, Mengcheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10157540/
https://www.ncbi.nlm.nih.gov/pubmed/36331299
http://dx.doi.org/10.3724/abbs.2022156

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10157540/
https://www.ncbi.nlm.nih.gov/pubmed/36331299
http://dx.doi.org/10.3724/abbs.2022156

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