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Assessment of Purity, Functionality, Stability, and Lipid Composition of Cyclofos-nAChR-Detergent Complexes from Torpedo californica Using Lipid Matrix and Macroscopic Electrophysiology

The main objective of the present study was to find detergents that can maintain the functionality and stability of the Torpedo californica nicotinic acetylcholine receptor (Tc-nAChR). We examined the functionality, stability, and purity analysis of affinity-purified Tc-nAChR solubilized in detergen...

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Detalles Bibliográficos
Autores principales: Quesada, Orestes, González-Nieves, Joel E., Colón, José, Maldonado-Hernández, Rafael, González-Freire, Carol, Acevedo-Cintrón, Jesús, Rosado-Millán, Irvin D., Lasalde-Dominicci, José A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10157581/
https://www.ncbi.nlm.nih.gov/pubmed/37140614
http://dx.doi.org/10.1007/s00232-023-00285-x