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The novel BRDT inhibitor NHWD870 shows potential as a male contraceptive in mice: A novel inhibition of BRDT for male contraception

Small molecule inhibitors of the bromodomain and extraterminal domain (BET) family proteins have emerged as promising options not only for the treatment of multiple cancers but also for disturbing the process of sperm maturation with potential for use as viable contraceptive targets. In this study,...

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Detalles Bibliográficos
Autores principales: Wu, Sixian, Li, Xiaoliang, Shang, Lijun, Wu, Lvying, Li, Tongtong, Li, Peiyv, Ji, Zhiliang, Hou, Jianwen, Yin, Mingzhu, Xu, Wenming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10157631/
https://www.ncbi.nlm.nih.gov/pubmed/36239350
http://dx.doi.org/10.3724/abbs.2022135