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The novel BRDT inhibitor NHWD870 shows potential as a male contraceptive in mice: A novel inhibition of BRDT for male contraception
Small molecule inhibitors of the bromodomain and extraterminal domain (BET) family proteins have emerged as promising options not only for the treatment of multiple cancers but also for disturbing the process of sperm maturation with potential for use as viable contraceptive targets. In this study,...
Autores principales: | Wu, Sixian, Li, Xiaoliang, Shang, Lijun, Wu, Lvying, Li, Tongtong, Li, Peiyv, Ji, Zhiliang, Hou, Jianwen, Yin, Mingzhu, Xu, Wenming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10157631/ https://www.ncbi.nlm.nih.gov/pubmed/36239350 http://dx.doi.org/10.3724/abbs.2022135 |
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