Development of a Cell-Based AlphaLISA Assay for High-Throughput Screening for Small Molecule Proteasome Modulators

[Image: see text] The balance between protein degradation and protein synthesis is a highly choreographed process generally called proteostasis. Most intracellular protein degradation occurs through the ubiquitin–proteasome system (UPS). This degradation takes place through either a ubiquitin-depend...

Descripción completa

Detalles Bibliográficos
Autores principales: Staerz, Sophia D., Lisabeth, Erika M., Njomen, Evert, Dexheimer, Thomas S., Neubig, Richard R., Tepe, Jetze J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10157846/
https://www.ncbi.nlm.nih.gov/pubmed/37151549
http://dx.doi.org/10.1021/acsomega.3c01158

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10157846/
https://www.ncbi.nlm.nih.gov/pubmed/37151549
http://dx.doi.org/10.1021/acsomega.3c01158

Ejemplares similares