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Development of a Cell-Based AlphaLISA Assay for High-Throughput Screening for Small Molecule Proteasome Modulators
[Image: see text] The balance between protein degradation and protein synthesis is a highly choreographed process generally called proteostasis. Most intracellular protein degradation occurs through the ubiquitin–proteasome system (UPS). This degradation takes place through either a ubiquitin-depend...
Autores principales: | Staerz, Sophia D., Lisabeth, Erika M., Njomen, Evert, Dexheimer, Thomas S., Neubig, Richard R., Tepe, Jetze J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10157846/ https://www.ncbi.nlm.nih.gov/pubmed/37151549 http://dx.doi.org/10.1021/acsomega.3c01158 |
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