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Clickable Shiga Toxin B Subunit for Drug Delivery in Cancer Therapy

[Image: see text] In recent years, receptor-mediated drug delivery has gained major attention in the treatment of cancer. The pathogen-derived Shiga Toxin B subunit (STxB) can be used as a carrier that detects the tumor-associated glycosphingolipid globotriaosylceramide (Gb3) receptors. While drug c...

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Detalles Bibliográficos
Autores principales: Danielewicz, Natalia, Rosato, Francesca, Tomisch, Jana, Gräber, Jonas, Wiltschi, Birgit, Striedner, Gerald, Römer, Winfried, Mairhofer, Juergen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10157870/
https://www.ncbi.nlm.nih.gov/pubmed/37151527
http://dx.doi.org/10.1021/acsomega.3c00667