Dual A(1) and A(2A) adenosine receptor antagonists, methoxy substituted 2-benzylidene-1-indanone, suppresses intestinal postprandial glucose and attenuates hyperglycaemia in fructose-streptozotocin diabetic rats

BACKGROUND/AIM: Recent research suggests that adenosine receptors (ARs) influence many of the metabolic abnormalities associated with diabetes. A non-xanthine benzylidene indanone derivative 2-(3,4-dihydroxybenzylidene)-4-methoxy-2,3-dihydro-1 H-inden-1-one (2-BI), has shown to exhibit higher affini...

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Detalles Bibliográficos
Autores principales: Sanni, Olakunle, Terre’Blanche, Gisella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10157944/
https://www.ncbi.nlm.nih.gov/pubmed/37143025
http://dx.doi.org/10.1186/s12902-023-01354-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10157944/
https://www.ncbi.nlm.nih.gov/pubmed/37143025
http://dx.doi.org/10.1186/s12902-023-01354-x

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