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Impacts of plasma microbial lipopolysaccharide translocation on B cell perturbations and anti-CD4 autoantibody production in people with HIV on suppressive antiretroviral therapy

BACKGROUND: . Up to 20% of people with HIV (PWH) who undergo virologically suppressed antiretroviral therapy (ART) fail to experience complete immune restoration. We recently reported that plasma anti-CD4 IgG (antiCD4IgG) autoantibodies from immune non-responders specifically deplete CD4 + T cells v...

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Detalles Bibliográficos
Autores principales: Fu, Xiaoyu, Cheng, Da, Luo, Zhenwu, Heath, Sonya L., Adekunle, Ruth, McKinnon, John E, Martin, Lisa, Sheng, Zizhang, Espinosa, Enrique, Jiang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10157945/
https://www.ncbi.nlm.nih.gov/pubmed/37138358
http://dx.doi.org/10.1186/s13578-023-01022-6