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Functional role and epithelial to mesenchymal transition of the miR-590-3p/MDM2 axis in hepatocellular carcinoma

BACKGROUND: There is considerable evidence that microRNAs (miRNAs) regulate several key tumor-associated genes/pathways and may themselves have a dual regulatory function either as tumor suppressors or oncogenic miRNA, depending on the tumor type. MicroRNA-590-3p (miR-590-3p) is a small non-coding R...

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Detalles Bibliográficos
Autores principales: Youssef, Alaa Ibrahem, Khaled, Gehad Mahmoud, Amleh, Asma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10157954/
https://www.ncbi.nlm.nih.gov/pubmed/37138218
http://dx.doi.org/10.1186/s12885-023-10861-y