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Piperlongumine inhibits proliferation and oncogenic MYCN expression in chemoresistant metastatic retinoblastoma cells directly and through extracellular vesicles

Ocular retinoblastoma malignancies, which develop into metastatic phenotypes, result in poor prognosis and survival for infant and child patients. To improve the prognosis of metastatic retinoblastoma, it is important to identify novel compounds with less toxic side effects and higher therapeutic ef...

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Detalles Bibliográficos
Autores principales: Shi, Cui, Huang, Kunhui, Soto, John, Sankaran, Renuka, Kalia, Vrinda, Onwumere, Onyekwere, Young, Michael, Einbond, Linda, Redenti, Stephen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10157982/
https://www.ncbi.nlm.nih.gov/pubmed/36940616
http://dx.doi.org/10.1016/j.biopha.2023.114554